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Ailin Cabrera

 


Ailin Cabrera

Master in Stomatology, Master in Epidemiology
Universidad Peruana Cayetano Heredia, Lima, Peru

 

Most Important Achievement

I am proud of having obtained the Hipolito Unanue Award for the best scientific publication (as a coauthor) in Dentistry twice.

Professional aspirations

My short-term goal is to develop a line of research on pediatric oral health at the Dental School of UPCH, where I work as an assistant professor. I would also like to do collaborative research with other health professionals to introduce oral health in general health care programs.

 

KUSKAYA RESEARCH PROJECT
 
Developmental Defects of Enamel in Children Prenatally Exposed to Antiretroviral Therapy
 
Mother to child transmission of HIV has significantly decreased with the establishment of antiretroviral treatment protocols during pregnancy. On the other hand, some medications during pregnancy could alter enamel formation of primary teeth, increasing the risk of early childhood caries. However, it is unknown if antiretroviral therapy (ART) could cause developmental enamel defects (DED). The aim of the study is to assess the effect that prenatal exposure to ART has on developing DED in the primary teeth of exposed infants.
 
A retrospective cohort study will be conducted and 345 children between 12 and 24 months old will be included (115 infants exposed to ART and 230 unexposed) from 5 major public hospitals in Lima, Peru. Data regarding prenatal exposure to ART and other factors related to pregnancy (HIV status, other diseases, and medications) will be recorded from maternal clinical charts. Developmental enamel defects in infants will be measured with a clinical evaluation, using the modified DED index. Multivariate analysis will be performed using generalized lineal models to model relative risk. The model will be adjusted for confounding factors selected a priori.
 
Specific aims:
1. Determine the prevalence and severity of DDE in primary teeth in the exposed and unexposed groups.
2. Determine the frequency of DDE per type of tooth and type of defect.
3. Determine and describe the frequency of prenatal risk factors for DDE in primary teeth in the exposed and unexposed groups.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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